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Micro-Manager versions

Micro-Manager 2.0 is the actively developed, current, version of Micro-Manager that you should use unless there is functionality in 1.4 that you need. 1.4 is no longer developed (except for the ASI diSPIM plugin). Nightly builds are usually fine to use, and have the latest features and bug fixes. If you encounter a bug in a release version, always test with the latest nightly build to see if the bug has been fixed already.

Micro-Manager 2.0.0 (July 13, 2021)

Due to security features of macOS 10.12 and later, Micro-Manager may not start when opening ImageJ.app. To circumvent this, within the Micro-Manager folder in Applications, hold command and drag ImageJ onto the desktop. Then hold command and drag it back in. Then try running again. In addition, you need to CTRL-click or right-click and select Open (instead of simply double-clicking) the first time you open it. See Installation Notes.

Partial list of differences with 1.4

  • Completely re-designed API
  • Better looking User Interface with Day/Night skins
  • Pycro-Manager
  • User Profiles (settings can be saved per user)
  • Image Inspector with overlays (time stamps, Size bar)
  • Versatile viewer with build-in Projection
  • ClearVolume 3D viewer integration
  • Export as displayed to ImageJ

Nightly Builds

Nightly builds are almost always stable and a better choice for most users than the latest official release.

Older nightly builds:

Micro-Manager 1.4.23 (June 30, 2021)

Requires Windows 7-10. Windows 10 recommended. Device drivers may have other requirements.

Requires Mac OS X 10.5 or greater. Device drivers may have other requirements.
(if the application does not open when double-clicked for the first time, try ctrl-click or right click, then select “Open”.)

Micro-Manager 1.4.22 (August 14, 2015)

Read the Known Issues.

Requires Windows XP, or 7-10. Windows 7 recommended. Device drivers may have other requirements.

Requires Mac OS X 10.5-10.10. 10.11 (El Capitan) is not yet supported. Device drivers may have other requirements.
(OS X 10.8 and later: if the application does not open when double-clicked for the first time, try ctrl-click or right click, then select “Open”.)

Known issues in 1.4.22

  • If you use AndorSDK3 (Andor sCMOS cameras) and experience a crash upon starting Micro-Manager (or loading a hardware configuration), please upgrade to the 20150820 nightly build (Windows 64-bit, Windows 32-bit)
  • Olympus IX83 users: please use 1.4.21 instead.

Changes in 1.4.22 (since 1.4.21)

  • Bugfixes and enhancements in the main application
    • Fix a hang when restarting MDA with data processors installed while Live mode is running (Mark Tsuchida)
    • When adding Z stage devices, the user may now specify the directionality of the stage (whether positive or negative directions move closer to the sample)
    • Fix a bug with storage of user configuration data on Windows 8 and later operating systems (Chris Weisiger)
    • Bugfixes relating to saved data:
      • Fix a minor bug in formatting of metadata in multipage TIFF files (Mark Tsuchida)
      • Fix a bug causing truncation of OME Medatada (Chris Weisiger)
      • Fix a memory leak noticeable when running acquisitions with large position lists (Chris Weisiger)
    • Display bugfixes:
      • Fix a bug causing RGB channels to be swapped when loading files (Chris Weisiger)
      • Fix display of total timepoints in cancelled acquisitions (Chris Weisiger)
    • Fix a bug in behavior of slider controls in European locales (Mark Tsuchida)
    • Fix a NullPointerException when the logfile directory is missing (Mark Tsuchida)
    • Fix a NullPointerException in the Metadata panel (Nico Stuurman)
    • Correctly remember autofocus parameters in preferences (Mark Tsuchida)
    • Enable high-resolution rendering on Macs with Retina Displays
    • Add setting for focus stage coordinate polarity in Hardware Configuration Wizard (Mark Tsuchida)
  • New plugins
    • Mightex Polygon, for controlling the Polygon patterned illuminator devices
  • Updated plugins
    • ASIdiSPIM: numerous bugfixes and improvements (Jon Daniels, Nico Stuurman)
    • Projector: numerous bugfixes and improvements (Jon Daniels, Nico Stuurman)
    • HCS Site Generator
      • Improved acquisition pathing within a well, using a snakelike route (Nico Stuurman)
      • add support for 6- and 12-well plates (Thomas Petebauer, Chris Weisiger)
  • Autofocus plugins
    • Added NullAutofocus, an autofocus method that does nothing, useful in certain complex acquisitions (Mark Tsuchida)
  • New device adapters
    • CNCMicroscope adapters (David Konerding)
      • ArduinoNeoPixel: Adafruit NeoPixel sheild as a shutter
      • RAMPS: RepRap RAMPS/Marlin motor drivers as XY and Z stage
    • Diskovery: Andor Diskovery multi-modal imaging system (Nico Stuurman)
    • Standa8SMC4: An alternative Standa stage adapter using the XIMC motion control library (Eugene Seliverstov)
  • Updated device adapters
    • Andor: Update Andor DLLs; add iXon 888 isolated crop ROIs; support FVB mode; add hardware timestamps on compatible cameras; fix Exposure display (Matthew Milford, Andor)
    • AndorSDK3: Allow fast exposure switching for Snap; allow switching on/off static blemish correction; add shutter control properties (Matthew Milford and Francis McCloy, Andor)
    • AndorShamrock: Add Rayleigh wavelength property; other fixes (Francis McCloy, Andor)
    • ASITiger: Support SetOriginX/Y; updates to scanner and PLogic; hardware sequencing support for piezo (Jon Daniels, ASI)
    • Cobolt: Fix a serial communication issue (Mark Tsuchida)
    • GigECamera: Avoid an error while connecting with some cameras (Mark Tsuchida)
    • IIDC: Add limited/experimental color camera support (Mark Tsuchida)
    • LeicaDMI: Add fixed shutter delay setting (Egor Zindy); fix turret control issues with DMi8 (Mark Tsuchida)
    • Marzhauser: Fix potential serial communication issue (Falk Dettmar, Marzhauser)
    • Mightex_C_Cam: Updates (JT Zheng, Mightex)
    • NI100X (National Instruments): Add support for hardware-triggered sequencing (Chris Weisiger)
    • OpenCVgrabber: update from OpenCV 2.4.8 to 2.4.9 on OS X (Mark Tsuchida)
    • PCO_Camera: Fix issue when using software trigger mode with pco.camera (Franz Reitner, PCO)
    • PI: Fix serial connection issue with certain controllers (Mark Tsuchida)
    • PICAM: Allow use of multiple cameras (Mark Tsuchida)
    • PVCAM: Fix a crash when enabling Color during Live; fix a possible Snap failure after changing binning and ROI; prevent timeout with slow cameras (Photometrics)
    • Prior: Fix a communication issue with certain controllers (Mark Tsuchida)
    • Sapphire: Fix a serial communication issue (Mark Tsuchida)
    • SpectralLMM5: Add FLICR (PWM) and fiber output selection support (Nico Stuurman)
    • StandaStage: Disable limit switch setting causing issues with some setups (Ed Simmons)
    • SutterLambda: Add setting for filter wheel timeout (Nico Stuurman)
    • XIMEA: Fix crash upon Snap; use camera timestamp resetting only for applicable cameras; add missing GPO port modes for MU USB2 (Marian Zajko, XIMEA)
    • Yokogawa CSU22, CSUX, CSUW1: Fix a possible hang; speed no longer a state device (Pariksheet Nanda)
    • ZeissCAN: Fix problem while disconnecting when connected by USB (Nico Stuurman)
  • New closed-source device adapters
    • MightexPolygon: Mightex Polygon multiwavelength patterned illuminators (Mightex)
  • Updated closed-source device adapters
    • HamamatsuHam: Fix ROI coordinates when binning enabled (Nico Stuurman)
    • Olympus: Fix Focus Sensitivity setting (Mark Tsuchida)
    • OlympusIX83: Prevent reporting incorrect stage position immediately after move (Mark Tsuchida)
    • RaptorEPIX: Add support for OWL640, Ninox and Eagle cameras (David Biggs)
  • Changes of interest to developers
    • Micro-Manager 1.4.22 is SVN trunk r15693, 3rdparty r176.
    • All but a few of the Java dependency JARs are now fetched from Maven repositories using Ivy, rather than using the copy in 3rdpartypublic/classext (Mark Tsuchida)
    • Add an unregisterForEvents() method to the gui (ScriptInterface) API (Henry Pinkard)
    • MMCore API changes
      • Add methods setOriginX(), setOriginY() for XY stages that allow zeroing X and Y independently (Mark Tsuchida)
      • The home() and stop() method now also work with Z/focus stages (where supported) (Mark Tsuchida)
      • Add methods setFocusDirection(), getFocusDirection(), allowing to store and retrieve focus stage coorinate polarity where known. Explicitly set values are recorded in hardware configuration file (Mark Tsuchida)
      • Add methods getGalvoXMinimum(), getGalvoYMinimum() (Nico Stuurman)
    • MMDevice interface changes
      • Add optional methods to set X and Y origin separately for XY stages (SetXOrigin() and SetYOrigin()) (Mark Tsuchida)
      • Add optional Home() and Stop() methods to Z/focus stages (Mark Tsuchida)
      • Add optional GetFocusDirection() to Z/focus stages (Mark Tsuchida)
      • Add GetXMinimum(), GetYMinimum() methods to galvo device (Nico Stuurman)
      • The HubID property is now read-only (Nico Stuurman)
  • Miscellaneous
    • Added a MATLAB script, StartMMStudio.m that configures and starts MMStudio (Windows only) (Mark Tsuchida)

(Previous releases)